Apr 01, 2022
Magnolol is a plant polyphenolic substance from the Magnolia Bark Extract Powder. It is a secondary metabolite produced by plants and has anti-inflammatory, antioxidant and chronic disease prevention functions.
Many studies have found that magnolia bark honokiol has various antioxidant properties, such as direct scavenging of free radicals and enhancement of antioxidant enzyme activity.
Oxidative stress refers to an imbalance between the production of free radicals and the homeostasis of the antioxidant system. It causes damage to cellular components, including lipids, nucleic acids, proteins, and carbohydrates, leading to tissue damage. Honokiol can prevent oxidative stress by activating the body's antioxidant system to reduce the generation of free radicals and scavenge free radicals, mainly by antioxidant enzymes, such as SOD, GSH-Px and CAT.
Honokiol exerts its anti-inflammatory function by activating or inhibiting various signaling molecules. Studies have shown that honokiol can inhibit the activation of inflammatory-related signaling pathways such as nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) by regulating a variety of extracellular signals. In turn, it regulates the transcription level of inflammation-related genes and exerts anti-inflammatory functions.
3. Antibacterial function
As a botanical fungicide, magnolia bark extract honokiol has broad-spectrum antibacterial activity and strong antibacterial function both in vitro and in vivo, which can inhibit bacterial proliferation and infection.
In recent years, plant polyphenols such as honokiol have shown the function of preventing and inhibiting various malignant tumors in cancer research. It can play an anti-cancer effect by promoting the apoptosis pathway of cancer cells and inhibiting their cell proliferation, migration and invasion. In vitro studies have shown that honokiol has inhibitory effects on glioblastoma, colon cancer, cervical cancer, gallbladder cancer and other cancer cells.
Magnolia bark extract powder has anti-inflammatory, antioxidant and anti-aging properties. Therefore, Magnolia bark can prevent and treat various oxidative stress-induced inflammatory diseases, and long-term application may have the effect of preventing the occurrence and development of body aging.
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