How Does Bitter Gourd Extract Work for Diabetes？

Bitter Melon Extract Powder contains Momordica glucoside. It has a peculiar bitter taste. Bitter melon also has the title of "the crown of bitterness" in fruits and vegetables. The bitter taste is believed to be effective in preventing diabetes and treating related complications.

Bitter Melon Extract And Diabetes

A sedentary lifestyle, high dietary energy intake, and obesity are among the various causes of metabolic syndrome and diabetes. The role of diet and dietary interventions has been highlighted in many scientific studies, with the role of plants and their products being significant.

The bioactive components extracted from fresh bitter gourd have similar structure and physicochemical indexes to insulin. It has a significant effect of regulating blood sugar. Its possible mechanism of action is to regulate blood sugar by activating insulin, activating insulin receptors, and improving the effective utilization of insulin. Bitter melon exerts its hypoglycemic effect through different modes of action and mechanisms, namely:

①Repair damaged islet beta cells, improve insulin level and sensitivity;

②By inhibiting glucosidase, it inhibits the absorption of glucose and inhibits the activity of disaccharides to play a hypoglycemic effect;

③ Decrease the secretion of apolipoprotein C-III and apolipoprotein B (Apo-B), and increase the synthesis of Apo lipoprotein A-1 (Apo A-1), which is the basic protein component necessary for HDL synthesis. It play a role in reducing The role of cholesterol and triglyceride levels.

Summary

The p-insulin from Bitter Melon Extract Powder significantly reduces blood sugar levels, similar to insulin's inhibition of glucose absorption by inhibiting the activity of glucosidase. Steroidal saponins can effectively control blood sugar levels, and have the effects of peptides and alkaloids, which can effectively control blood sugar levels.