Does Olive Leaf Have Oleuropein?

The active ingredient in olive leaves extract powder was the highest content of polyphenolic compound Oleuropein (OLE). OLE is a polyphenolic compound with a natural split iridoid skeleton, which can be absorbed and utilized by the body. Its safety has been confirmed in animal experiments and clinical studies.

Content and distribution of oleuropein

The content of oleuropein is mainly affected by its source and extraction method. Extraction methods include conventional and unconventional extraction methods.

Conventional extraction methods include cold solvent extraction, solvent extraction and Soxhlet extraction.

Unconventional extraction methods include ultrasonic-assisted extraction, liquid-liquid extraction, microwave-assisted extraction, membrane extraction, pressurized fluid extraction, infrared-assisted extraction optimization, supercritical fluid extraction, microfluidic systems, acid hydrolysis, and solid-liquid extraction.

The main sources of oleuropein are olive leaf extract, olive leaf, olive fruit, olive stone and olive rhizome. Among them, the content of oleuropein in olive leaf extract was higher, and the content ranged from 15.66 to 905.96 mg/g (dry weight).

In addition, the content of oleuropein determined in various literatures varies greatly, which may be related to the area and time of collection of raw materials, as well as the different extraction methods.

What is the benefit of oleuropein?

Oleuropein has a variety of biological activities, can participate in the body's metabolic process, and can relieve and treat a variety of common diseases. OLE has biological activities such as antioxidant, anti-inflammatory and anti-apoptotic. It can regulate body metabolism, regulate gene expression, and change enzyme activity, thereby improving common human diseases such as hyperglycemia, hypertension, hyperlipidemia, obesity and cancer, and has protective and repairing effects on various organs.