What Is Mulberry Leaf Extract Good For?

The wide range of physiological activities of DNJ in Natural Mulberry Leaf Extract. It can not only effectively treat diabetes and its complications, but also improve the health of the body. Moreover, the toxicity and side effects are very low, and it has a good application prospect.

1. Lowering blood sugar and blood lipids

DNJ is an alkaloid with a sugar-like structure. It can effectively inhibit the activity of α-glucosidase, and significantly reduces the fasting blood sugar and postprandial blood sugar peak of the human body. At present, many biopharmaceutical companies in China have developed and marketed new drugs for regulating blood sugar and blood lipids or losing weight using DNJ as raw materials. There are also dozens of companies specializing in the production of DNJ extracts. Its superior pharmacological activity has broad prospects for its industrialization as a hypoglycemic and lipid-lowering food and drug ingredient. However, in terms of the effect of DNJ on hypoglycemia and blood lipids, most scholars still focus on the comparison of its blood glucose, various blood lipid indicators, and related enzyme activities, but its specific inhibitory pathways and mechanisms have not been in-depth.

2. Anti-virus, anti-tumor

DNJ has a strong inhibitory effect on viral activity. It has certain developmental potential in the treatment of AIDS and viral hepatitis. DNJ disrupts glycosylation of gp120 by hindering glycoprotein processing. This blocks or reduces HIV-induced syncytiogenesis, interrupting HIV penetration and spread. In addition, through the study of the activity of DNJ and its derivatives against hepatitis B virus (HBV) in vitro, it was found that DNJ has a more obvious anti-HBV effect in vitro.