Cortex Dictamni Extract

English name: Cortex Dictamni Extract

Specification: 10:1, 20:1

Use Part: root bark

Appearance: Pale brown powder

Mesh size: 80 Mesh

Test Method: TLC

1. Antibacterial effect: In vitro test 1:4 aqueous extract has different degrees of inhibition on various pathogenic fungi such as Trichophyton rubrum, Concentric Trichophyton, and Xanthomonas oryzae, but there are reports The ether, ethanol and water extracts of the product had no effect on the cocci, such as E. coli, Pseudomonas aeruginosa and M. grisea. 1:20 decoction has no killing effect on Trichomonas vaginalis.

2. Effects on the cardiovascular system and blood: The chalk contained in this product has an excitatory effect on the isolated frog heart in a small amount, which can increase the myocardial tension and increase the minute output and the amount of the bolus. It has obvious contraction effect on the blood vessels of isolated rabbit ears. The jatropha contains an antiarrhythmic effect, and the muscarinic has an ephedrine-like effect, which can increase the blood pressure of the anesthetized cat, enhance the contraction of the nictitating membrane of the cat, dilate the coronary artery, and enhance the activating effect of adrenaline.

3. Effects on uterus and intestinal smooth muscle: berberine has a strong contraction effect on rabbit and guinea pig uterine smooth muscle. Innyl can also strengthen the uterus contraction of cat or rabbit, strengthen the influence of adrenaline on the uterus, and make up There is no effect on the spontaneous contraction of rat uterus, but the uterine contraction induced by oxytocin can be attenuated, while the muscarine can be enhanced. Insulin can inhibit the contraction of small intestine, jalapine can inhibit the ileal sputum in rabbits caused by strontium chloride, and jasmine and alkaloids can also relax the Oddi's sphincter. It has been reported that white alkali and arbutin A mixture of alkaloids and the like has a stronger antispasmodic effect on rats and guinea pigs than a single alkaloid.

4. Anti-cancer effect: Eosin staining results show that the non-polar solvent extract and volatile oil of this product have anti-cancer activity in vitro, and quercetin, white fresh alkali and one kind of volatile oil are isolated from the ether extract of this product. The color transparent liquid is an effective component for anticancer activity in vitro, and its concentration of 45% can kill Ehrlich ascites carcinoma, S180 and U14 cells, while phbodone, limonin and β-sitosterol are ineffective.

5. Dictamnus albus L. The root bark has an antipyretic effect, and oral administration of its decoction to rabbits with fever (warm-sting method) can reduce body temperature. The dog is intravenously injected with another white fresh skin D. Albus var. Caucasicus extract, which can shorten the blood coagulation time.

6. Other effects: a mixture of white alkali, muscarinic and jalapine can reduce the effect of adrenaline on the seminal vesicle of guinea pigs. Oncine can cause muscle paralysis and can cause a progressive decline in blood pressure in mammals due to involvement of the myocardium. Insulin can increase the tension of striated muscle and strengthen the excitability of spinal cord reflex. The pharmacological activity of fenugreek is weak. However, it has been reported in early years that it can reduce the nerve value in neuromuscular specimens, and the time value of muscles decreases first and then increases. In addition, fenugreek has a certain anti-cancer effect, 12.5mg / kg can extend the life of P388 leukemia mice by 31%.

Certificate of Analysis

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