What Does Wild Yam Extract Do?

Traditional Chinese medicine believes that Wild Yam Extract Powder has the functions of relaxing tendons, promoting blood circulation, expectorating phlegm, and digesting food. Modern pharmacological studies have shown that it has anti-inflammatory, hypolipidemic, hypoglycemic and other effects. This article reviews its pharmacological effects.

1. Anti-inflammatory effect

Pro-inflammatory cytokines are secreted by immune cells, and sustained inflammatory cytokine release and response lead to chronic inflammation that can cause a variety of diseases. Molecular mechanism of diosgenin, the active ingredient in wild yam extract, improving inflammation in human umbilical vein endothelial cells. Diosgenin regulates TLR2/MyD88 by

Signaling pathways play a protective role in systemic inflammatory response syndrome.

2. Anti-tumor effect

Numerous studies have shown that dioscin has antitumor activity against various tumors, such as lung cancer, gastric cancer, colon cancer, ovarian cancer, breast cancer, etc. In the study of the therapeutic mechanism of skin cancer, dioscin has a significant effect on apoptosis and DNA damage.

3. Hypoglycemic effect

It has been proved by animal models that yam extract can significantly reduce the steady-state insulin resistance model assessment and fat insulin resistance value, suggesting that dioscin has the effect of reducing insulin resistance. In addition, it was found that diosgenin significantly reduced insulin resistance in adipose tissue through the IRS1/PI3K/Akt pathway, and it is expected to become a new therapeutic drug for insulin resistance.

4. Lowering blood lipids

Hyperlipidemia often accompanies obesity and other diseases such as fatty liver.

Galloside can reduce body weight and liver lipid accumulation symptoms in experimental mice, and increase oxygen consumption and energy consumption. By promoting fatty acid β-oxidation, down-regulating MAPK phosphorylation levels, inducing autophagy, and inhibiting triglyceride and cholesterol synthesis. Thereby it alleviates fatty liver and prevents obesity caused by diet.

Summary

Dioscorea saponin has a wide range of pharmacological effects, has the advantages of good curative effect and few side effects, and its application in clinical treatment has far-reaching significance. With the gradual deepening of scientific research, the application of Wild Yam Extract Powder will be more extensive, the mechanism of action will be more determined, and it will provide medicinal value for more diseases.