Mar 06, 2022
Angelica is rich in volatile oils, organic acids, polysaccharides, and other active ingredients. Its root powder, extracts, and active ingredient ferulic acid have attracted extensive attention as cosmetic efficacy raw materials in the beauty industry. This article will review the anti-aging effects of Angelica Sinensis extract.
Skin aging is the most easily observed appearance change in the human aging process, manifested as skin relaxation, decreased elasticity, increased wrinkles, decreased luster and tenderness, etc., caused by free radicals, telomerase, genetics mitochondrial damage, etc. It is the result of the combined action of exogenous factors such as photoaging and environmental pollution.
Angelica volatile oil can effectively increase the secretion of collagen type I (Col-I) from human dermal fibroblasts (HDF-α). Angelica Sinensis water extract can reduce the content of LF, MDA, type III collagen, the apoptosis rate, and Bax protein expression in skin fibroblasts, increase the content of type I collagen and HYP, and improve the cell proliferation ability and the expression of SOD, GSH-Px active. At the same time, it has the ability to scavenge DPPH free radicals and complex ferrous ions. All these suggest that Angelica Sinensis water extract can play an anti-aging effect on the skin by promoting the proliferation of skin fibroblasts, improving the antioxidant capacity and inhibiting the apoptosis of skin cells. The alcoholic extract of Angelica Sinensis also can scavenge DPPH free radicals and complex ferrous ions.
In addition, Sun et al. treated human dermal fibroblasts by adding ethanol extract of Angelica Sinensis immediately after UVB irradiation. Results The alcoholic extract of Angelica Sinensis could reduce the expression of MMP-1 and MMP-3. It can resist UVB photoaging by restoring the synthesis of type I procollagen and reducing the pro-inflammatory cytokine IL-6. Angelica polysaccharide has DPPH free radical scavenging effect, and ferulic acid can make the skin delicate, soft and shiny.
To sum up, the volatile oil, water extract, alcohol extract, polysaccharide and ferulic acid of Angelica Sinensis all have a good effect on delaying skin aging. With the continuous growth of the economy and the continuous improvement of living conditions, people's pursuit of greenness and advocating nature is constantly strengthening, and the demand for natural health cosmetics is increasing. The purchasing trend is gradually changing from basic products to functional products with complex functions. . angelica gigas root extract has a good application prospect in anti-aging cosmetics.
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