Hot Sale Celandine Extract Powder 10:1

Product name: celandine extract

Latin Name: Chelidonium majus

Test method: HPLC

Specification: 10:1

Appearance: Light brown Powder

Effect on muscles

It is chemically similar to papaverine, and its action is similar. It can inhibit various smooth muscles and has antispasmodic effect, while its toxicity is low. It is a direct effect on the inhibition of smooth muscle, because it can not only fight against pilocarpine, but also counteract the effects of histamine or even strontium chloride (pilocarpine, celandine total base), and the effect on the isolated small intestine of rabbits. The weight is about 53% of the papaverine, and the celandine injection can also relieve the contraction of the guinea pig isolated intestinal tube caused by the antigen-antibody reaction. It has also been reported that low concentrations can increase the tension of isolated rabbit intestines and uterus, while higher concentrations inhibit, and large doses can inhibit myocardium, slow heart rate, stop in dilatation, and also inhibit striated muscle. The total alkaloids of celandine are stimulating to smooth muscle.

Effect on the nervous system

Chrysanthemum is a class of proto-opodine that also inhibits the central nervous system. Compared with morphine, it has a stronger effect on the distal end, but is weaker on the central part, and has some analgesic and hypnotic effects. The celandine injection can inhibit the central activity of the mice and reduce the spontaneous activity. The method and acetic acid writhing method showed an analgesic effect on mice.

The therapeutic dose does not inhibit breathing, and a large amount can be slowed down; there is no obvious inhibition of reflex, and there is no spinal cord excitability; it can paralyze the sensation and motor nerve endings, but has no effect on the nerve trunk.

Anti-tumor effect

Chelerythrine is a mitotic bacterium that can change the middle and late division index of hypertriplokd in transplanted ascites cancer cells in mice, showing a significant blocking effect. After administration of 125mg/kg 12 In the hour, 23.1% stopped in the mid-term division; 2.5×10(-6)M in vitro inhibited the mitosis of fibroblasts. Can delay the growth of malignant tumors. Although it inhibits mouse sarcoma-180 and Ai's tumor, it has side effects and toxicity. The original opioid also has an anti-cancer effect.

It has also been reported that the anticancer effect of chelerythrine and protopine is not obvious, while 40% of the methanol extract of celandine has obvious anticancer activity; there is a celandine extract for mouse lymphocytic leukemia L1210 and Rat sarcoma W256 has no inhibitory effect, but it is cytotoxic to Eagles PKB nasopharyngeal carcinoma cells in tissue culture, and one of the components that produce cytotoxicity is coptisine. No effect on murine Jensen sarcoma.

other

After a short-term anesthesia caused by blood root alkalosis, it can cause convulsions of the spleen, increase intestinal peristalsis and salivation, and then stimulate the local area and then transfer to paralysis; it can also reduce the activity of cholinesterase and increase the tissue to acetylcholine. Sensitivity improves the tension of the small intestine and uterine smooth muscle. Α-high chelerythrine is similar to chelerythrine; β-high chelerythrine is scorpion venom and has local anesthetic effect. Polysporine (Paheka) has ganglion blockade and enhances the function of the uterus, which can enhance the inhibition process of the central nervous system (conditional reflex and EEG test). The chelerythrine and some kind of Stilbylamine may be related to the ability of the plant to remove skin blemishes. These ingredients are very variable when the plant is dry. The berberine in celandine is a kind of cytotoxicity, and berberine may be related to its antibacterial and choleretic.

Total alkali can inhibit Gram-positive bacteria, Mycobacterium tuberculosis, fungi, etc. in vitro. The concentrations of protopine, erythromycin and chelerythrine 716.7 μg/ml inhibited Kaufman-Wolf's Trichophyton and F. oxysporum. In addition, it contains some unknown ingredients that can excite the heart, raise blood pressure, and expand coronary vessels.

Certificate of Analysis

1.Pharmaceutical raw materials and stuff;

2.Beverage for hearlth care;

3.Healthy food additive

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