What is the mechanism of action of Senna?

Some of the vital functions of Senna leaves are purgative bowels and heat, easing food retention, and arresting internal bleeding. It is an effective cure for indigestion, bloating, gastroduodenal ulcer, edema and habitual constipation.

anthraquinoneSenna has anthraquinone derivatives or glycosides that work by irritating the colon, stimulating peristalsis and subsequent evacuation of stools. Senna may also help enhance stool volume by smoothing the muscles and preventing water and electrolyte re-absorption.

Because it is a powerful laxative, Senna leaf has a lapactic effect, which is one of the reasons why it is used in colon cleansing and detoxification. It also cures constipation, bloating, irritable bowel syndrome, and hemorrhoids. Its purgative actions can promote weight loss by excreting fats and toxins through the digestive system.