What Is Honokiol Good For?

Oct 28, 2021

What Is Honokiol Good For?

Honokiol is extracted from the bark of a kind of magnolia tree. In the definition of medicine, it has the functions of sterilization, anti-inflammatory and anti-tumor. Magnolia Officinalis is native to the valleys of China, and its bark can be obtained from roots, stems, and branches. If only a small amount of concentration is used, it will act as an antiseptic in the field of skincare.


Honokiol is derived from biphenol compounds and is the main active ingredient of the traditional Chinese medicine Magnolia Officinalis. It was first isolated from Japanese magnolia in 1930. It is a traditional Chinese medicine for dispelling dampness. It has a pungent and bitter taste and is warm in nature. Its effect is mainly to dispel dampness, and is used when excessive moisture hinders the middle coke. It is derived from dry flower buds and is picked at the end of spring and dried in the sun or at low temperatures. It is a fine brown or white powder with a fragrant smell, which is a more pungent ingredient and bitter. It is a colorless needle-like crystal with a melting point of 102°C. Soluble in benzene, ether, chloroform, acetone and common organic solvents. The benefits of honokiol to people are as follows:

(1) Antibacterial effect

Honokiol has obvious antibacterial effect. Honokiol has the lowest inhibitory concentration against Candida, Microsporum, Microphylla, Aspergillus niger, Cryptococcus neoformans and Candida albicans, and against Bacillus subtilis and Mycobacterium smegmatis The minimum inhibitory concentration. Honokiol has the effects of killing oral bacteria and eliminating bad breath, and has become one of the main components of menthol and chewing gum.

(2) Anti-inflammatory effect

Honokiol can inhibit lymphocyte germination, mouse ear swelling, reduce the permeability of the capillary wall at the inflammation site, and inhibit leukocyte migration and fibrous tissue proliferation in a dose-dependent manner. It can also change the cytokine pattern of inflammation-related diseases, reduce inflammatory factors, and increase the production of anti-inflammatory factors. The anti-inflammatory effect may be related to the inhibition of the AA metabolic pathway and inhibition of intracellular lysosome release. The results showed that free radicals in neutrophils reduced the concentration of superoxide anions produced by 1-109M/L. When the concentration is greater than 109M/L, it significantly inhibits the release of β-glucosidase and lysozyme, and activates neutrophils. cell. In addition, free radicals can reduce sepsis caused by gastroenteritis.

In short, honokiol has many benefits for us. It has antibacterial and anti-inflammatory effects, and it is also a classic prescription for treating depression in Chinese medicine. It also has certain effects in the treatment of emotional distress.

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