Pine bark extract with high antioxidant capacity-proanthocyanidins

Jul 09, 2021

Pine bark extract is a class of substances extracted from pine bark. The pine bark peeled from the tree is collected, flattened and extracted. It contains a lot of compounds called OPCs (procyanidin oligomers). Since the French scientist Dr. Jack Meskelly separated OPCs from peanut shells in 1947, OPCs have been found in many plants. A large number of studies on it have proved that OPCs are effective antioxidants, and are non-toxic, non-mutagenic, non-carcinogenic and have no side effects. Very safe to use. Pine bark has been proven to be a new source of OPCs. The OPCs extracted from pine bark have no difference in quality and function, except for some slight differences in appearance.

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Features

The antioxidant capacity of pine bark extract comes from proanthocyanidins (oligomers of proanthocyanidins) (OPCs). The antioxidant capacity of this substance is 20 times that of vitamin C and 50 times that of vitamin E. As well-known antioxidants, OPCs can effectively suppress the effects of free radicals, and free radicals play an important role in degenerative diseases, cardiovascular diseases, blurred vision, sunburn and premature aging.
1. Cardiovascular disease
Research confirms that OPCs can help strengthen the strength of capillaries, arteries and veins, which endow them with many important clinical applications. OPCs can be used to stabilize blood vessel walls, inhibit inflammation, and mainly support tissues containing collagen and elastin.
a) Arteriosclerosis
It has been confirmed that the oxidant LDL plays an important role in causing arteriosclerosis. Due to the excellent antioxidant function of OPCs, it can eliminate the damage of free radicals to the arterial wall like collagenase and elastase, thereby preventing or repairing arteriosclerosis. Animal experiments show that OPCs can slow down or repair arteriosclerosis.
b) Venous insufficiency (varices)
Varicose veins easily occur when blood pools in the legs, and can cause pain, heaviness, edema, fatigue, and swelling of the veins. By strengthening capillary strength and reducing capillary permeability, OPCs can reduce the pain and edema of venous insufficiency. For the same reason, OPCs are recommended as excellent treatments for hemorrhoids. There are indications that OPCs also have a good effect on edema caused by injuries and surgery. OPCs can speed up the elimination of edema by repairing damaged blood vessels and lymphatic vessels that have lost fluid.
A double-blind controlled drug test involving 92 people showed that taking 100mg OPCs three times a day can significantly improve the main symptoms including heaviness, edema and foot discomfort. After a period of one month, 75% of patients who received OPCs showed adequate improvement in symptoms. Another controlled drug test involving 364 individuals also showed that the results of treatment with OPCs far exceeded the placebo group.
c) Retinopathy/improvement of vision
The ability of OPCs to strengthen the strength of capillaries and reduce permeability is very effective for patients suffering from stroke and retinopathy. OPCs have been proven to be effective in improving retinopathy caused by diabetes, arteriosclerosis, inflammation and aging. It has also been reported that OPCs can accelerate the recovery of vision after strong light and improve the visual acuity of patients with visual fatigue caused by long-term computer use.
A 6-week controlled (but not blind) study evaluated the ability of grape skin (seed) OPCs to improve night vision in ordinary subjects. In this trial, the night vision and strong flash recovery ability of 100 healthy volunteers who received 200 mg OPCs per day showed a significant increase compared with the control group who did not receive the drug.
2. Aging/Alzheimer's disease
Because OPCs can easily pass through the blood-brain barrier and effectively inhibit the damage of free radicals to the brain tissue, it can effectively prevent and improve Alzheimer's disease.
3. Skin care
Due to its antioxidant capacity, OPCs are believed to protect the skin from excess UV radiation and free radical damage. A lot of evidence shows that OPCs protect and strengthen the collagen and elastin in the skin, thereby preventing wrinkles and maintaining skin elasticity. Adding OPCs to facial creams is a popular way to delay skin aging. In theory, repairing skin collagen and elastin can rejuvenate the skin.
4. Anti-cancer, anti-inflammatory and anti-allergic
Because free radicals play an important role in the formation of tumors, OPCs can be used in appropriate amounts to exert their anti-cancer effects. At the same time, because it effectively inhibits inflammatory factors such as PG, 5-HT and leukotrienes, and selectively combines with connective voxels in joints to relieve pain and edema, OPCs have a certain effect on a variety of arthritis. . The anti-allergic activity of OPCs is believed to be the result of their antihistamine activity. Compared with other anti-allergic drugs, OPCs have the same efficacy but no side effects such as drowsiness.

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