Combing the effects of Polygonum multiflorum extract!

Mar 19, 2021

Polygonum multiflorum extract is the dried root tuber of Polygonum multiflorum. Its main functional components are lecithin, emodin, rhein and other components. Main functions: anti-aging effect, influence on the immune system, hypolipidemic and anti-atherosclerotic effect, myocardial protective effect, hepatoprotective effect, neuroprotective effect, antibacterial effect.

Polygonum multiflorum extract


Anti-aging effect

A large amount of lipid peroxidation products are accumulated in aging animals, and the activity of superoxide dismutase is reduced. Experimental results show that Polygonum multiflorum can significantly reduce the content of malondialdehyde in the brain and liver tissues of old mice, increase the content of monoamine transmitters in the brain, and enhance the activity of SOD. It can also significantly inhibit the monoamine oxidase-B in the brain and liver tissues of old mice. Activity, thereby eliminating the damage of free radicals to the body, delaying the occurrence of aging and diseases.

Impact on the immune system

Polygonum multiflorum can antagonize the atrophy and degeneration of mouse thymus caused by the immunosuppressant hydrocortisone or prednisolone, increase the weight of its thymus, adrenal gland, spleen and abdominal lymph nodes, increase the total number of white blood cells, and promote the phagocytosis of abdominal macrophages , Reduce the content of circulating immune complexes in mice.

Lowering blood lipid and anti-atherosclerosis effect

Polygonum multiflorum can resist atherosclerosis.

Myocardial protection

Studies have found that Polygonum multiflorum extract has a preventive effect on myocardial ischemia reperfusion injury in dogs.

Hepatoprotective effect

The stilbene glycosides contained in Polygonum multiflorum have a significant antagonistic effect on the fatty liver and liver function damage caused by peroxidized corn oil in rats, the increase of liver lipid peroxide content, and the increase of serum alanine aminotransferase and aspartate aminotransferase. Can significantly reduce serum free fatty acids and liver lipid peroxides.


The main active ingredient in Polygonum multiflorum: stilbene glycosides has a significant antagonistic effect on the decrease of neuronal survival rate caused by β-amyloid and hydrogen peroxide and the increase of lactate dehydrogenase leakage.

Antibacterial effect

The decoction of different processed products of Polygonum multiflorum is effective against Staphylococcus aureus, Staphylococcus albicans, Shigella flexneri, Shigella sonnei, Bacillus typhi 901, Bacillus paratyphi B, Bacillus diphtheria, Streptococcus beta-hemolyticus, Neskertal Bacteria have different degrees of inhibition. Among them, the decoction of raw Shouwu has stronger anti-Staphylococcus aureus effect than other processed products, and the decoction of Shouwu has stronger effect on Staphylococcus albicans, the decoction of Shouwu with wine and rehmannia glutinosa juice. Steamed Shouwu decoction is better than raw products and other processed products in inhibiting diphtheria bacilli.

Other effects

The anthraquinone derivatives contained in Polygonum multiflorum can promote intestinal peristalsis and have a mild diarrhea effect.

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