Arbutin vs. Kojic Acid Dipalmitate: Which is Better for Whitening?

Apr 20, 2022

Kojic acid Dipalmitate and arbutin are popular skin lightening ingredients. Both of them work by inhibiting the activity of tyrosinase. So, do you know which of the two is better?


Skin Lightening Mechanism

Skin color is mainly determined by the amount of melanin in the skin. Melanin is synthesized in melanocytes. Normally, melanocytes are present in the basal layer of the epidermis. In melanocytes, melanin is combined with a protein matrix to form melanosomes. In melanin granules, tyrosinase converts tyrosine into normal melanin (eumelanin) or brown melanin (pheomelanin).

Skin lightening agents can block or even reverse melanin biosynthesis. Therefore, it can be used to lighten or lighten human skin. Skin lightening agents can also be used to treat localized hyperpigmentation or spots due to excessive local melanin synthesis or uneven distribution.

Arbutin vs. Kojic Acid Dipalmitate


Kojic Acid Dipalmitate



Whitening, Moisturizing


Tyrosinase Inhibitor

Tyrosinase Inhibitor

Ease of Recipe















1. ++++++: Max value

2. -/+: Min value

3.-: Negative value


Obviously, in these two kinds of skin lightening agents. Kojic acid dipalmitate is the latest development and offers the best functionality. Also, in addition to being a skin lightening agent, kojic acid dipalmitate is a moisturizing agent. Arbutin may be incompatible with some sunscreens and preservatives due to its potential hydrogen bonding. Kojic acid dipalmitate is fully compatible with all sunscreens and preservatives. Therefore, it is the "first choice" in cosmetic formulations for skin lightening.

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