May 12, 2021
Cassia seed is the seed of "cassia", a commonly used traditional Chinese medicine. The seed is used as medicine, which has the functions of clearing liver, improving eyesight and laxative. Indications of hypertension, headache, dizziness, acute conjunctivitis, corneal ulcers, glaucoma, carbuncle sores and sores. Using its leaves to make tea, long-term drinking for middle-aged and elderly people, can normalize blood pressure and smooth stool. Cassia is extremely vigorous in plant communities and often competes with other plants for nutrition. Therefore, in North America and other regions, Cassia is regarded as a weed that is difficult to eradicate.
Cassia seed is also known as "returning pupil". Cassia seed contains a variety of vitamins and is rich in amino acids, fats, carbohydrates, etc. In recent years, its health care function has attracted increasing attention. Cassia seed has the functions of clearing liver fire, dispelling rheumatism, benefiting kidney and improving eyesight. Drinking Cassia seed tea often can normalize blood pressure, smooth stools, and prevent presbyopia. Clinical experiments have proved that drinking cassia seed tea can clear the liver and improve eyesight, prevent blurred vision, lower blood pressure, lower blood fat, reduce cholesterol, etc. It has a good effect on the prevention and treatment of coronary heart disease and high blood pressure; and cassia seed is rich in vitamin A and zinc. Prevent night blindness and avoid zinc deficiency in children. In addition, the function of cassia seed tea to moisturize the bowel can also solve the problems of modern people's gastrointestinal and constipation, can treat dry stool and help smooth defecation. The brewing method of cassia seed tea is very simple. Just use 15-20 grams of cassia seed to brew with hot water. You can also add an appropriate amount of sugar according to personal preference. Drink it as a tea, several times a day, if it can be served with medlar and chrysanthemum , The effect is better.
1. Antibacterial effect: Cassia seed alcohol extract has inhibitory effect on staphylococcus, diphtheria bacillus, cassia vulgaris, paratyphoid bacillus, and Escherichia coli, while water extract is ineffective.
2. Anti-fungal: The water immersion agent is diluted in a test tube, and 1:20 has an inhibitory effect on Microsporum odendron, and 1:10 has an inhibitory effect on Flavus vulgaris and Microsporum gypsum.
3. Antihypertensive: Water extract and ethanol extract have antihypertensive effect on anesthetized dogs, cats and rabbits.
4. Lowering blood lipids: 6g of Cassia Seed Decoction or Cassia Seed Powder/feeding rats for 8 weeks can reduce plasma cholesterol and triglycerides in experimental hyperlipidemia rats, and reduce the content of triglycerides in the liver.
5. Anti-platelet aggregation: Cassia decoction or powder 6g/kg fed to rats for 8 weeks can inhibit the platelet aggregation induced by ADP in rats.
6. The effect on immune function. Subcutaneous injection of 15g/kg Cassia Seed Decoction and Alcohol Precipitation Agent can make mouse thymus atrophy, and the negative rate of ANAE staining of peripheral blood lymphocytes will be significantly reduced, so that 2,4-dinitrochlorobenzene (DNCB) The delayed-type hypersensitivity reaction of mouse skin is inhibited, but it has no obvious effect on the formation of serum hemolysin. In addition, the cassia seed water decoction alcohol precipitation agent can significantly increase the percentage of mouse peritoneal macrophages and the phagocytic index of chicken red blood cells, and the level of lysozyme. It is also significantly higher than the control group.
7. Hepatoprotective effect: Oral 670mg/kg of Cassia seed hot water extract has weak detoxification effect on the liver of mice poisoned by carbon tetrachloride. The cassia seed was defatted with petroleum ether, extracted with chloroform, and then extracted with methanol. As a result, the methanol extract has a significant liver-protecting effect. It was further divided into chrysophanol-lO-triglucoside and chrysophanol-1-O-tetraglucoside at 1mg/ml, which have weak protective effect on liver cells damaged by carbon tetrachloride, and it was also found that aloe-emodin also has similar effects. The anti-hepatotoxic effect.
8. Laxative effect Cassia seed has a laxative effect. The diarrhea effect of its liquid extract reaches its peak in 3-5 hours after oral administration. Obtain the 50% ethanol soluble part from the water decoction, and then use ethyl acetate and butyric acid to obtain the soluble part and the water-soluble part respectively. Separate several components of the butanol part with the highest purgative activity with a dextran gel column, and hydrolyze the active components with acid to obtain the same chrysophanol, dianthrone and d-glucose. After oral administration of these components, the condensate of nitrosodiphenylamine and chrysophanol anthrone can be detected in the large intestine, but for mice treated with chloramphenicol to inhibit the proliferation of intestinal bacteria, its laxative activity was reduced by half. Anthrone production is also reduced.
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